BT-20 Blend: BPC-157 and TB-500 in One Vial
The classic research pairing in one vial. Why BPC-157 and TB-500 are studied together, and how to do the math.
| Contents | BPC-157 10 mg + TB-500 10 mg |
|---|---|
| Total peptide | 20 mg per vial |
| Ratio | 1 : 1 |
| Research on the blend itself | None published. Evidence is per component |
| Hero product | BT-20 |
BPC-157 and TB-500 are probably the most commonly paired research peptides. BT-20 puts 10 mg of each in a single vial. Like any blend, it has no published research of its own. The rationale comes from studies of each peptide separately.
This guide explains why the two are paired, how they differ, and how the 1:1 math works.
Origin story: two different repair pathways
| BPC-157 | TB-500 | |
|---|---|---|
| Source | Gastric juice protein fragment | Thymosin beta-4 fragment |
| Main pathways | VEGFR2, FAK–paxillin, nitric oxide | Actin binding, cell migration |
| Key models | Tendon, gut, blood vessels (rodent) | Skin wounds, heart (rodent) |
Because the pathways don’t overlap much, researchers interested in repair models often look at both together.
Reconstitution math
At 1:1, both peptides always have the same concentration.
| Water added | Each peptide | Units for 250 mcg of each |
|---|---|---|
| 2 mL | 5 mg/mL | 5 units |
| 3 mL | 3.33 mg/mL | 7.5 units |
| 4 mL | 2.5 mg/mL | 10 units |
Enter 10 mg (one component) in the peptide calculator to get units. Follow the reconstitution guide for technique.
Weak spots: what we don’t know
- No combination studies have been published.
- Fixed ratio. Use separate vials if a study needs to vary one peptide.
- Human data for either peptide are very limited.
BT-20 FAQ
What does BT-20 stand for?
BPC-157 + TB-500, 20 mg total.
BT-20 or GLOW?
GLOW adds 50 mg of GHK-Cu for copper and collagen research. See the GLOW guide.
What is Hero BT-20?
A 20 mg lyophilized research blend of BPC-157 and TB-500, for laboratory research use only.
References
- Chang CH, et al. The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration. J Appl Physiol. 2011;110(3):774-780.
- Gwyer D, Wragg NM, Wilson SL. Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing. Cell Tissue Res. 2019;377(2):153-159.
- Goldstein AL, Hannappel E, Kleinman HK. Thymosin β4: actin-sequestering protein moonlights to repair injured tissues. Trends Mol Med. 2005;11(9):421-429.
For laboratory research use only. Not for human or veterinary use. This article summarizes published research and is not medical advice.